Join us to make history

Responsibilities

Ractigen Therapeutics, founded by the pioneers of a paradigm-shifting technology known as RNAa, is the leading RNAa-based pharmaceutical company, located in a modern biotech industry park of Nantong City of Jiangsu Province (2 h drive from Shanghai), China. We are seeking highly motivated and creative talents at all career levels with the qualifications specified below to join an international team of scientists to brining into market ground-breaking medicines for many severely unmet clinical needs. Particularly, we welcome qualified individuals from outside of China to apply.

The positions to be filled are:

• Director/Principal Scientist/Senior Scientist/Scientist, Cell/molecular biology, HTS and lead discovery/optimization
• Principal Scientist/Senior Scientist/Scientist, Oncology/immuno-oncology, genetic diseases
• Senior Director/Director/Principal Scientist, in vivo and/or in vitro Pharmacology, ADME/DMPK
• Director/Principal Scientist/Senior Scientist, in Medicinal chemistry/nucleic acid chemistry, formulation development for oligonucleotide delivery (lipid nanoparticle- and conjugation-based)

Benefits:

• Working in a stimulating environment and with an international team of scientists and entrepreneurs;
• Excellent physical working environment with recreation area and equipment
• Free/subsidized housing;
• Internationally competitive salaries with a generous benefit package including bonus and stock options;
• Talent incentives provided by local governments and competitive talent programs for qualified individuals.
• Unique experience of working in China, and particularly in Yangtze River Delta Economic Zone which is poised to become the World’s epic center for drug development.

Requirements

• Ph.D./M.D. in life sciences with Postdoc, or MS in life science with minimum 5+ years of relevant experience and distinguished publication record;
• The candidates should have a solid background in one of the following areas: cell/molecular biology, oncology and immune-oncology, nucleic acid/oligonucleotide chemistry, oligonucleotide-based drug development, oligonucleotide formulation development, IND-enabling development of oligonucleotide drugs;
• You are willing to lead and orchestrate a group of scientists with diverse expertise in a multidisciplinary drug discovery program;
• You have previous experience in oligonucleotide drug discovery from hit identification to lead optimization and pre-clinical studies;
• You have a strong experience in a biotechnology or pharmaceutical environment;
• You are science-driven, result-oriented, and should demonstrate technical proficiency, scientific creativity;
• You should demonstrate collaboration/team spirit and excellent verbal and written communication skills (English);
• Track record of scientific success demonstrated by authorship on publications in excellent journals, and/ or patents.

Responsibilities

1. Perform animal experiments and some other experiments arranged by the supervisor.
2. Establish tumor animal models (subcutaneous implantation).
3. Perform drug administration, measurement and data analysis.
 

Requirements

1. Master degree or above in biomedical science.
2. Experience of cell biology, zoology and preclinical studies.
3. Experience of establishing various animal models especially tumor animal models is preferred.
4. Skilled in animal experiments such as intravenous administration, cell culture, histopathology, nucleic acid isolation, mRNA/protein expression analysis and FACS.
5. Excellent communication and learning skills, strong responsibility, practical capacity and teamwork spirit.
 

Responsibilities

1. Perform primary cell culture and make the cell lines stably passage. 
2. Do high throughput RNAi screening (HTS) based on lentivirus and some other HTS. 
3. Perform transfection, vector construction, molecular cloning, mRNA/gene expression analysis and FACS.
4. Participate in projects related to discovery and validation of saRNA candidates. 
 

Requirements

1. Master degree or above in biomedical science; with experience of research on cell/molecular biology.
2. Skilled in transfection, vector construction, molecular cloning, mRNA/gene expression analysis and FACS.
3. Spirit of adventure, innovation and teamwork. 
4. Excellent communication and learning skills, as well as good compressive capacity.
 

Responsibilities

1. Perform molecular design and optimization for saRNA gene activation systems. 
2. Establish high throughput RNAi screening systems based on lentivirus and new high throughput screening (HTS) systems based on shRNA. 
3. Analyze and design various nucleic acid and protein sequences.
 

Requirements

1. Master's degree in biomedical science. Postdoctoral experience of cell/molecular biology, synthetic biology or transcription/epigenetic regulation is preferred.
2. Skilled in molecular cloning, report gene analysis, cell culture, RNA technology, nucleic acid isolation, and mRNA/protein expression analysis. 
3. Spirit of adventure, innovation and teamwork. 
4. Excellent communication and learning skills, as well as good compressive capacity.